[HTML][HTML] Mechanical devices of the spliceosome: motors, clocks, springs, and things

JP Staley, C Guthrie - Cell, 1998 - cell.com
JP Staley, C Guthrie
Cell, 1998cell.com
). Although introns needed to be removed with single-nucleotide precision to avoid
introducing catastrophic errors of frame, they contained few conserved sequences, varied
widely in length, and were found at dozens of locations in a single transcript. How did cells
achieve this exquisite precision while splicing such diverse introns?
). Although introns needed to be removed with single-nucleotide precision to avoid introducing catastrophic errors of frame, they contained few conserved sequences, varied widely in length, and were found at dozens of locations in a single transcript. How did cells achieve this exquisite precision while splicing such diverse introns?
cell.com