[HTML][HTML] The other Janus face of Qa-1 and HLA-E: diverse peptide repertoires in times of stress
T van Hall, CC Oliveira, SA Joosten… - Microbes and infection, 2010 - Elsevier
The non-polymorphic MHC molecule Qa-1 and its human counterpart HLA-E present
monomorphic signal peptides to innate receptors and thereby regulate lymphocyte activity.
Under stress, this peptide content is replaced with a surprisingly diverse repertoire of novel
peptides that are associated with heat-shock proteins, infectious agents or antigen
processing defects.
monomorphic signal peptides to innate receptors and thereby regulate lymphocyte activity.
Under stress, this peptide content is replaced with a surprisingly diverse repertoire of novel
peptides that are associated with heat-shock proteins, infectious agents or antigen
processing defects.
