Do memory CD4 T cells keep their cell-type programming: plasticity versus fate commitment? T-cell heterogeneity, plasticity, and selection in humans
Cold Spring Harbor perspectives in biology, 2018•cshperspectives.cshlp.org
The wide range of effector and memory T cells is instrumental for immune regulation and
tailored mechanisms of protection against pathogens. Here, we will focus on human CD4 T
cells and discuss T-cell plasticity and intraclonal diversification in the context of a
progressive and selective model of CD4 T-cell differentiation.
tailored mechanisms of protection against pathogens. Here, we will focus on human CD4 T
cells and discuss T-cell plasticity and intraclonal diversification in the context of a
progressive and selective model of CD4 T-cell differentiation.
The wide range of effector and memory T cells is instrumental for immune regulation and tailored mechanisms of protection against pathogens. Here, we will focus on human CD4 T cells and discuss T-cell plasticity and intraclonal diversification in the context of a progressive and selective model of CD4 T-cell differentiation.
cshperspectives.cshlp.org