[PDF][PDF] Asthma is associated with increased mortality in individuals with sickle cell anemia
JH Boyd, EA Macklin, RC Strunk, MR DeBaun - 2007 - digitalcommons.wustl.edu
An analysis of a prospective cohort of individuals with sickle cell anemia (SCA), enrolled
from birth through adulthood, was conducted to determine if asthma is a risk factor for death
in SCA. All-cause mortality was determined for participants after adjusting for known risk
factors for death in SCA. The study included 1,963 individuals who were followed for 18,495
patient-years. After controlling for established risk factors, individuals with SCA and asthma
had a more than two-fold higher risk of mortality (hazard ratio 2.36, 95% CI 1.21 to 4.62, p …
from birth through adulthood, was conducted to determine if asthma is a risk factor for death
in SCA. All-cause mortality was determined for participants after adjusting for known risk
factors for death in SCA. The study included 1,963 individuals who were followed for 18,495
patient-years. After controlling for established risk factors, individuals with SCA and asthma
had a more than two-fold higher risk of mortality (hazard ratio 2.36, 95% CI 1.21 to 4.62, p …