HDL cholesterol transport during inflammation
DR van der Westhuyzen, FC de Beer… - Current opinion in …, 2007 - journals.lww.com
DR van der Westhuyzen, FC de Beer, NR Webb
Current opinion in lipidology, 2007•journals.lww.comCurrent data support a model for the acute phase response in which serum amyloid A and
sPLA 2-IIa, present at sites of inflammation and tissue damage, play a protective role by
enhancing cellular cholesterol efflux, thereby promoting the removal of excess cholesterol
from macrophages.
sPLA 2-IIa, present at sites of inflammation and tissue damage, play a protective role by
enhancing cellular cholesterol efflux, thereby promoting the removal of excess cholesterol
from macrophages.
Summary
Current data support a model for the acute phase response in which serum amyloid A and sPLA 2-IIa, present at sites of inflammation and tissue damage, play a protective role by enhancing cellular cholesterol efflux, thereby promoting the removal of excess cholesterol from macrophages.
Lippincott Williams & Wilkins