Prevention of radiation induced xerostomia by surgical transfer of submandibular salivary gland into the submental space
N Jha, H Seikaly, J Harris, D Williams, R Liu… - Radiotherapy and …, 2003 - Elsevier
Backgroundandpurpose: Xerostomia is a significant morbidity of radiation treatment in the
management of head and neck cancers. We hypothesized that the surgical transfer of one
submandibular salivary gland to the submental space, where it can be shielded from
radiation treatment (XRT), would prevent xerostomia. Materialsand methods: We conducted
a prospective Phase II clinical trial and the patients were followed clinically with salivary flow
studies and the University of Washington Quality of Life questionnaire. Results: We report …
management of head and neck cancers. We hypothesized that the surgical transfer of one
submandibular salivary gland to the submental space, where it can be shielded from
radiation treatment (XRT), would prevent xerostomia. Materialsand methods: We conducted
a prospective Phase II clinical trial and the patients were followed clinically with salivary flow
studies and the University of Washington Quality of Life questionnaire. Results: We report …
