Combined C3b and factor B autoantibodies and MPGN type II
Q Chen, D Müller, B Rudolph… - … England Journal of …, 2011 - Mass Medical Soc
Q Chen, D Müller, B Rudolph, A Hartmann, E Kuwertz-Bröking, K Wu, M Kirschfink, C Skerka…
New England Journal of Medicine, 2011•Mass Medical SocCombined C3b and Factor B Autoantibodies and MPGN Type II | NEJM Skip to main content
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This letter describes two unrelated patients with membranoproliferative glomerulonephritis type 2 and autoantibodies to the two individual components of C3 convertase, factor B and C3. These autoantibodies enhance C3 convertase activity, probably leading to nephritis.
The New England Journal Of Medicine