Epidemiology and natural history of hepatocellular carcinoma
KA McGlynn, WT London - Best practice & research Clinical …, 2005 - Elsevier
Hepatocellular carcinoma (HCC) is a major contributor to cancer incidence and mortality.
There is a wide variation, however, in the global distribution of HCC. Eighty percent of the
burden is borne by countries in Asia and sub-Saharan Africa. In most high-risk countries,
principal risk factors include infection with hepatitis B virus and dietary exposure to aflatoxin
B1. In contrast, hepatitis C virus and alcohol consumption are more important risk factors in
low-risk countries. In recent years, the incidence of HCC has decreased in some high-risk …
There is a wide variation, however, in the global distribution of HCC. Eighty percent of the
burden is borne by countries in Asia and sub-Saharan Africa. In most high-risk countries,
principal risk factors include infection with hepatitis B virus and dietary exposure to aflatoxin
B1. In contrast, hepatitis C virus and alcohol consumption are more important risk factors in
low-risk countries. In recent years, the incidence of HCC has decreased in some high-risk …
