Polydipsia and abolition of angiotensin-induced drinking after transections of subfornical organ efferent projections in the rat
R Eng, RR Miselis - Brain Research, 1981 - Elsevier
R Eng, RR Miselis
Brain Research, 1981•ElsevierRats with transections of subfornical organ (SFO) efferent projections failed to drink to
intravenous angiotensin-II (AII) but responded to intracellular dehydration and water
deprivation and suppressed drinking when food deprived. However, the transected rats
were polydipsic and polyuric. Thus SFO efferent projections mediate AII-induced drinking
and may be involved in the regulation of body fluid balance.
intravenous angiotensin-II (AII) but responded to intracellular dehydration and water
deprivation and suppressed drinking when food deprived. However, the transected rats
were polydipsic and polyuric. Thus SFO efferent projections mediate AII-induced drinking
and may be involved in the regulation of body fluid balance.
Abstract
Rats with transections of subfornical organ (SFO) efferent projections failed to drink to intravenous angiotensin-II (AII) but responded to intracellular dehydration and water deprivation and suppressed drinking when food deprived. However, the transected rats were polydipsic and polyuric. Thus SFO efferent projections mediate AII-induced drinking and may be involved in the regulation of body fluid balance.
Elsevier
