A cartilage explant system for studies on aggrecan structure, biosynthesis and catabolism in discrete zones of the mammalian growth plate
AHK Plaas, JD Sandy - Matrix, 1993 - Elsevier
The structure, biosynthesis and catabolism of aggrecan has been studied in the bovine fetal
rib growth plate. Comparative analyses were made on six 1-mm transverse slices which
represent the resting zone (slice 6), proliferative zone (slices 5 and 4), upper hypertrophic
zone (slice 3), middle hypertrophic zone (slice 2) and lower hypertrophic zone (slice 1).
Aggrecan was abundant and exhibited very high aggregability in all zones. The aggrecan
monomer was similar in structure in the resting and proliferative zones but showed a marked …
rib growth plate. Comparative analyses were made on six 1-mm transverse slices which
represent the resting zone (slice 6), proliferative zone (slices 5 and 4), upper hypertrophic
zone (slice 3), middle hypertrophic zone (slice 2) and lower hypertrophic zone (slice 1).
Aggrecan was abundant and exhibited very high aggregability in all zones. The aggrecan
monomer was similar in structure in the resting and proliferative zones but showed a marked …
