Nephritogenicity of anti-proteoglycan antibodies in experimental murine lupus nephritis.
N Kashihara, H Makino, Z Szekanecz… - … ; a Journal of …, 1992 - europepmc.org
N Kashihara, H Makino, Z Szekanecz, CR Waltenbaugh, YS Kanwar
Laboratory Investigation; a Journal of Technical Methods and Pathology, 1992•europepmc.orgBackground Cross-reactivity between anti-DNA antibodies and heparan sulfate
(HS)/heparan sulfate-proteoglycan (HS-PG) of glomerular basement membrane has been
previously reported. Conceivably, this determines the final outcome of glomerular injury in
lupus nephritis.
(HS)/heparan sulfate-proteoglycan (HS-PG) of glomerular basement membrane has been
previously reported. Conceivably, this determines the final outcome of glomerular injury in
lupus nephritis.
Background
Cross-reactivity between anti-DNA antibodies and heparan sulfate (HS)/heparan sulfate-proteoglycan (HS-PG) of glomerular basement membrane has been previously reported. Conceivably, this determines the final outcome of glomerular injury in lupus nephritis.
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