The regulation of glucose effectiveness: how glucose modulates its own production
J Tonelli, P Kishore, DE Lee… - Current Opinion in Clinical …, 2005 - journals.lww.com
J Tonelli, P Kishore, DE Lee, M Hawkins
Current Opinion in Clinical Nutrition & Metabolic Care, 2005•journals.lww.comThe regulation of glucose effectiveness involves a complex interplay of hormonal and
metabolic factors, with free fatty acid and glucoregulatory hormones playing key roles. The
loss of this regulation in type 2 diabetes mellitus contributes importantly to hyperglycemia,
and may largely be caused by increased free fatty acid levels.
metabolic factors, with free fatty acid and glucoregulatory hormones playing key roles. The
loss of this regulation in type 2 diabetes mellitus contributes importantly to hyperglycemia,
and may largely be caused by increased free fatty acid levels.
Summary
The regulation of glucose effectiveness involves a complex interplay of hormonal and metabolic factors, with free fatty acid and glucoregulatory hormones playing key roles. The loss of this regulation in type 2 diabetes mellitus contributes importantly to hyperglycemia, and may largely be caused by increased free fatty acid levels.
Lippincott Williams & Wilkins