[HTML][HTML] In vivo tyrosine phosphorylation sites of activated ephrin-B1 and ephB2 from neural tissue
MS Kalo, HH Yu, EB Pasquale - Journal of Biological Chemistry, 2001 - ASBMB
EphB2 is a receptor tyrosine kinase of the Eph family and ephrin-B1 is one of its
transmembrane ligands. In the embryo, EphB2 and ephrin-B1 participate in neuronal axon
guidance, neural crest cell migration, the formation of blood vessels, and the development of
facial structures and the inner ear. Interestingly, EphB2 and ephrin-B1 can both signal
through their cytoplasmic domains and become tyrosine-phosphorylated when bound to
each other. Tyrosine phosphorylation regulates EphB2 signaling and likely also ephrin-B1 …
transmembrane ligands. In the embryo, EphB2 and ephrin-B1 participate in neuronal axon
guidance, neural crest cell migration, the formation of blood vessels, and the development of
facial structures and the inner ear. Interestingly, EphB2 and ephrin-B1 can both signal
through their cytoplasmic domains and become tyrosine-phosphorylated when bound to
each other. Tyrosine phosphorylation regulates EphB2 signaling and likely also ephrin-B1 …