[HTML][HTML] Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells

K Hirata, T Ishida, K Penta, M Rezaee, E Yang… - Journal of Biological …, 2001 - ASBMB
To gain fundamental information regarding the molecular basis of endothelial cell adhesive
interactions during vascular formation, we have cloned and characterized a unique cell
adhesion molecule. This molecule, named endothelial cell-selective adhesion molecule
(ESAM), is a new member of the immunoglobulin superfamily. The conceptual protein
encoded by cDNA clones consists of V-type and C2-type immunoglobulin domains as well
as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic …