[HTML][HTML] Determination of N-and C-terminal borders of the transmembrane domain of integrin subunits

A Stefansson, A Armulik, IM Nilsson… - Journal of Biological …, 2004 - ASBMB
Previous studies on the membrane-cytoplasm interphase of human integrin subunits have
shown that a conserved lysine in subunits α 2, α 5, β 1, and β 2 is embedded in the plasma
membrane in the absence of interacting proteins (Armulik, A., Nilsson, I., von Heijne, G., and
Johansson, S.(1999) in J. Biol. Chem. 274, 37030–37034). Using a glycosylation mapping
technique, we here show that α 10 and β 8, two subunits that deviate significantly from the
integrin consensus sequences in the membrane-proximal region, were found to have the …