Circulating levels of thrombopoietic and inflammatory cytokines in patients with clonal and reactive thrombocytosis

HC Hsu, WH Tsai, ML Jiang, CH Ho, ML Hsu… - Journal of Laboratory …, 1999 - Elsevier
The regulation of megakaryocytopoiesis and thrombopoiesis appears to be under the
control of an array of hematopoietic growth factors. To determine the relationship between
endogenous cytokine levels and circulating platelet counts, we measured the serum levels
of both thrombopoietic and inflammatory cytokines in the peripheral blood and bone marrow
samples from 70 patients with clonal thrombocytosis (CT) caused by myeloproliferative
disorders, 28 patients with reactive thrombocytosis (RT), and 35 normal control subjects. The …