Evaluation and treatment of severe and prolonged thrombocytopenia in neonates

MC Sola - Clinics in perinatology, 2004 - perinatology.theclinics.com
Some algorithms on the subject of neonatal thrombocytopenia have been based on the
suspected kinetic mechanism (increased platelet consumption versus decreased
production)[1, 2], and others have been based on the time of onset (early versus late
thrombocytopenia)[3–5]. We recently published recommendations for the evaluation of
thrombocytopenic neonates based on recognizing typical patterns of thrombocytopenia
associated with specific pathophysiologic processes:(1) immune,(2) infectious,(3) genetic,(4) …