Nutrient balance and energy expenditure during ad libitum feeding of high-fat and high-carbohydrate diets in humans

CD Thomas, JC Peters, GW Reed, NN Abumrad… - The American journal of …, 1992 - Elsevier
To study the influence of diet composition on regulation of body weight, we fed 21 weight-
stable subjects (11 lean, 10 obese) high-carbohydrate (HC) and high-fat (HF) diets for 1 wk
each. Although diet composition was fixed, total energy intake was unrestricted. Subjects
had a higher energy intake on the HF (11 039±2700 kJ/d) than on the HC (10 672±2617
kJ/d) diet (P< 0.05), but energy expenditure was not different between diets. On day 7 of the
HC diet, carbohydrate (CHO) oxidation was significantly related to CHO intake with the slope …