Quantitative 1H MRS in the evaluation of mesial temporal lobe epilepsy in vivo
CO Duc, AH Trabesinger, OM Weber, D Meier… - Magnetic resonance …, 1998 - Elsevier
Hippocampal metabolite concentrations were determined by localized in vivo proton
magnetic resonance spectroscopy (1H MRS) in eleven patients suffering from refractory
mesial temporal lobe epilepsy (MTLE), as well as in eleven age-matched healthy volunteers,
and compared with patient history, postoperative outcome and histopathology. Main results
are: 1) In patients, the decrease in N-acetylaspartate (NAA) concentrations was highly
significant ipsilateral, and less but still significant contralateral to the electroencephalogram …
magnetic resonance spectroscopy (1H MRS) in eleven patients suffering from refractory
mesial temporal lobe epilepsy (MTLE), as well as in eleven age-matched healthy volunteers,
and compared with patient history, postoperative outcome and histopathology. Main results
are: 1) In patients, the decrease in N-acetylaspartate (NAA) concentrations was highly
significant ipsilateral, and less but still significant contralateral to the electroencephalogram …