[HTML][HTML] The winged helix transcriptional activator HFH-3 is expressed in the distal tubules of embryonic and adult mouse kidney
DG Overdier, H Ye, RS Peterson, DE Clevidence… - Journal of Biological …, 1997 - ASBMB
The hepatocyte nuclear factor-3 (HNF-3)/fork head homolog (HFH) proteins are an extensive
family of transcription factors, which share homology in the winged helix DNA binding
domain. Members of the HFH/winged helix family have been implicated in cell fate
determination during pattern formation, in organogenesis, and in cell-type-specific gene
expression. In this study we isolated a full-length HFH-3 cDNA clone from a human kidney
library which encoded a 351-amino acid protein containing a centrally located winged helix …
family of transcription factors, which share homology in the winged helix DNA binding
domain. Members of the HFH/winged helix family have been implicated in cell fate
determination during pattern formation, in organogenesis, and in cell-type-specific gene
expression. In this study we isolated a full-length HFH-3 cDNA clone from a human kidney
library which encoded a 351-amino acid protein containing a centrally located winged helix …