Intercalated cell subtypes in connecting tubule and cortical collecting duct of rat and mouse
JIN Kim, YH Kim, JH Cha, CC Tisher… - Journal of the …, 1999 - journals.lww.com
At least two populations of intercalated cells, type A and type B, exist in the connecting
tubule (CNT), initial collecting tubule (ICT), and cortical collecting duct (CCD). Type A
intercalated cells secrete protons via an apical H+-ATPase and reabsorb bicarbonate by a
band 3-like Cl-/HCO 3-exchanger, AE1, located in the basolateral plasma membrane. Type
B intercalated cells secrete bicarbonate by an apical Cl-/HCO 3-exchanger that is distinct
from AE1 and remains to be identified. They express H+-ATPase in the basolateral plasma …
tubule (CNT), initial collecting tubule (ICT), and cortical collecting duct (CCD). Type A
intercalated cells secrete protons via an apical H+-ATPase and reabsorb bicarbonate by a
band 3-like Cl-/HCO 3-exchanger, AE1, located in the basolateral plasma membrane. Type
B intercalated cells secrete bicarbonate by an apical Cl-/HCO 3-exchanger that is distinct
from AE1 and remains to be identified. They express H+-ATPase in the basolateral plasma …