[HTML][HTML] Molecular Cloning of F4/80, a Murine Macrophage-restricted Cell Surface Glycoprotein with Homology to the G-protein-linked Transmembrane 7 Hormone …
AJ McKnight, AJ Macfarlane, P Dri, L Turley… - Journal of Biological …, 1996 - ASBMB
F4/80 is a monoclonal antibody that recognizes a murine macrophage-restricted cell surface
glycoprotein and has been extensively used to characterize macrophage populations in a
wide range of immunological studies. Apart from the tightly regulated pattern of expression
of the F4/80 antigen, little is known about its possible role in macrophage differentiation and
function. We have sought to characterize the molecule at the molecular level, through the
isolation of cDNA clones, and now describe the sequence of the F4/80 protein. The primary …
glycoprotein and has been extensively used to characterize macrophage populations in a
wide range of immunological studies. Apart from the tightly regulated pattern of expression
of the F4/80 antigen, little is known about its possible role in macrophage differentiation and
function. We have sought to characterize the molecule at the molecular level, through the
isolation of cDNA clones, and now describe the sequence of the F4/80 protein. The primary …