Involvement of polymorphisms in the chemokine system in the susceptibility for coronary artery disease (CAD). Coincidence of elevated Lp (a) and MCP-1− 2518 G/G …
C Szalai, J Duba, Z Prohászka, Á Kalina, T Szabó… - Atherosclerosis, 2001 - Elsevier
The central role of chemokines in the pathogenesis of atherosclerosis has been made clear.
Recently polymorphisms in the gene regulatory region of MCP-1 and in the promoter region
of RANTES have been found, which increase the expression of these chemokines. We
investigated the role of these polymorphisms together with the chemokine SDF-1− 801A and
the chemokine receptors CCR2-64I and CCR5Δ32 mutations in 318 patients with coronary
artery disease (CAD) referred to coronary bypass surgery, comparing them with 320 healthy …
Recently polymorphisms in the gene regulatory region of MCP-1 and in the promoter region
of RANTES have been found, which increase the expression of these chemokines. We
investigated the role of these polymorphisms together with the chemokine SDF-1− 801A and
the chemokine receptors CCR2-64I and CCR5Δ32 mutations in 318 patients with coronary
artery disease (CAD) referred to coronary bypass surgery, comparing them with 320 healthy …
