Irreversible progression of severe retinopathy in young type I insulin-dependent diabetes mellitus patients after improved metabolic control

CD Agardh, B Eckert, E Agardh - Journal of Diabetes and its Complications, 1992 - Elsevier
The impact of metabolic control on the development of rapidly progressive severe
retinopathy was studied in 14 young type I insulin-dependent diabetes mellitus (IDDM)
patients. Glycosylated hemoglobin (HbA lc) levels 45 months prior to and 12 months after
the diagnosis of retinopathy were compared with HbA lc levels in 17 type I IDDM patients
with no or minimal background retinopathy, matched for age and duration of diabetes. HbA
lc levels were generally higher in patients with severe retinopathy (p< 0.05) from 39 months …